2-(Methacryloyloxy)ethyl 2-(trimethylammonio)ethyl phosphate(CAS: 67881-98-5)

2-(Methacryloyloxy)ethyl 2-(trimethylammonio)ethyl phosphate has a crystalline form and a molecular weight of approximately 404.4 g/mol. It is poorly soluble in water but miscible with organic solvents like ethanol and methanol. The compound exhibits moderate reactivity, particularly in nucleophilic substitution reactions. It is non-volatile and has a pKa of around 4.5, indicating acidic properties.

2-(Methacryloyloxy)ethyl 2-(trimethylammonio)ethyl phosphate can be synthesized via a multi-step reaction involving methacrylic acid, trimethylamine, and phosphorus oxychloride. The reaction involves nucleophilic substitution and acylation steps, with tetra-n-butylammonium hydroxide as a catalyst. The yield is typically around 85%, and the reaction is carried out under mild heating conditions.

2-(Methacryloyloxy)ethyl 2-(trimethylammonio)ethyl phosphate is used in the pharmaceutical industry for the production of cationic polymers, in the polymer industry as a reactive surfactant, and in the sensor industry for developing ion-selective electrodes. It is also utilized in semiconductor manufacturing for surface treatments and in the cosmetics industry as a stabilizer and emulsifier.

When handling 2-(Methacryloyloxy)ethyl 2-(trimethylammonio)ethyl phosphate, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Store the compound in a dry, cool place away from direct sunlight. In case of spill, use appropriate spill containment materials and dispose of the waste according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.