3-Chloro-2-methylbenzoic acid(CAS: 7499-08-3)

3-Chloro-2-methylbenzoic acid is a white to off-white crystalline solid with a molecular weight of approximately 177.57 g/mol. It has a pKa of about 4.2 and is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. It exhibits moderate reactivity towards bases and nucleophiles.

3-Chloro-2-methylbenzoic acid is commonly synthesized through the nitration of toluene followed by reduction of the nitro group to a hydroxyl group, followed by chlorination. This process yields the desired compound with good selectivity and yield under appropriate conditions.

3-Chloro-2-methylbenzoic acid is used in various industries including pharmaceuticals for the synthesis of certain drugs, in the production of dyes and pigments, and as a precursor in the development of organic semiconductors. It also finds application in the synthesis of pesticides and other chemical intermediates.

When handling 3-Chloro-2-methylbenzoic acid, wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Store it in a cool, dry place away from heat sources and incompatible materials. Use a fume hood during operations to minimize inhalation exposure. Refer to the Safety Data Sheet (SDS) for detailed safety information.