2-butyl benzofuran(CAS: 4265-27-4)

2-Butyl benzofuran (CAS: 4265-27-4) is a colorless to light yellow liquid at room temperature. Its molecular weight is approximately 148.22 g/mol. It has a solubility of up to 10 g/L in water and is soluble in common organic solvents like ethanol and acetone. It is generally stable under normal conditions but may react with strong oxidizing agents.

2-Butyl benzofuran is typically synthesized by the reaction of benzaldehyde with 1-butanol in the presence of a strong acid like sulfuric acid as a catalyst. The reaction is exothermic and selective, yielding a high purity product with a yield of around 80%. The reaction mechanism involves the formation of an acyloin intermediate, followed by dehydration and rearrangement to form the desired benzofuran derivative.

2-Butyl benzofuran (CAS: 4265-27-4) is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of certain drugs; in the polymer industry, it is used in the production of polyurethane and other polymers; it also finds applications in the manufacturing of sensors and semiconductors due to its chemical properties.

When handling 2-butyl benzofuran (CAS: 4265-27-4), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation. Spills should be immediately cleaned up using absorbent materials, and the area should be rinsed with water. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.