2-Phenoxynicotinic acid(CAS: 35620-71-4)

2-Phenoxynicotinic acid is a white crystalline solid with a molecular weight of 226.24 g/mol. It has a solubility of about 1.5 g/L in water at 20°C. The compound is moderately reactive, particularly with reducing agents. It is stable in air and light but should be stored in a dry, cool place to avoid moisture and heat.

2-Phenoxynicotinic acid is typically synthesized by the condensation of 2-chloronicotinic acid and phenol. The reaction is usually carried out in the presence of a base such as potassium tert-butoxide, with a yield of around 80%. The reaction is exothermic and requires careful temperature control to achieve high selectivity and yield.

2-Phenoxynicotinic acid is used primarily in the pharmaceutical industry as an intermediate in the synthesis of various organic compounds. It is also utilized in the production of dyes and pigments. Additionally, it has applications in the manufacturing of some types of sensors and as a component in some polymer formulations.

When handling 2-Phenoxynicotinic acid, it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a cool, dry place, away from heat and moisture. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials. A safety data sheet (SDS) should be consulted for specific handling and disposal instructions.