Abiraterone Impurity 28(CAS: 114611-53-9)

Abiraterone Impurity 28 (CAS: 114611-53-9) is a crystalline compound with a molecular weight of approximately 446.58 g/mol. It has a solubility of about 1.2 mg/mL in water and exhibits moderate reactivity under basic conditions. This impurity is known for its stability under normal storage conditions, but it should be protected from moisture and heat to prevent degradation.

Abiraterone Impurity 28 (CAS: 114611-53-9) is synthesized through a multi-step process involving reduction, cyclization, and hydrogenation reactions. The synthesis typically uses palladium catalysts and involves the use of expensive starting materials. The overall yield is around 70%, with high selectivity towards the desired product.

Abiraterone Impurity 28 (CAS: 114611-53-9) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of abiraterone acetate, a medication for treating prostate cancer. It also finds limited use in research settings for studying the pharmacodynamics and metabolism of abiraterone acetate.

When handling Abiraterone Impurity 28 (CAS: 114611-53-9), always use appropriate personal protective equipment (PPE), including gloves, laboratory coat, and safety goggles. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using water and a suitable absorbent material. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.