N-Methyl-N-vinylacetamide(CAS: 3195-78-6)

N-Methyl-N-vinylacetamide (CAS: 3195-78-6) is a colorless to light yellow liquid with a molecular weight of approximately 122.13 g/mol. It has a solubility of up to 13.8 g/100 ml in water. This compound is moderately reactive, particularly towards nucleophiles. It is soluble in common organic solvents such as ethanol, acetone, and chloroform.

N-Methyl-N-vinylacetamide is typically synthesized through the reaction of acetic anhydride and vinylamine. The process involves the condensation of vinylamine with acetic anhydride under basic conditions. This method provides good yield and selectivity, with careful control of reaction conditions leading to a pure product.

N-Methyl-N-vinylacetamide (CAS: 3195-78-6) is primarily used in the pharmaceutical industry for the synthesis of various drug intermediates. It also finds applications in the polymer industry for the production of specific polymers and in the sensor industry for the development of gas sensors.

When handling N-Methyl-N-vinylacetamide (CAS: 3195-78-6), it is important to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. Ensure the work area is well-ventilated and use a fume hood to minimize exposure. Spills should be immediately cleaned up with sodium bicarbonate solution, and the area should be flushed with water. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.