1-Chloro-3-ethynylbenzene(CAS: 766-83-6)

1-Chloro-3-ethynylbenzene (CAS: 766-83-6) is a crystalline solid with a molecular weight of approximately 133.57 g/mol. It has a low solubility in water but is more soluble in organic solvents such as ethanol and acetone. Chemically, it is relatively stable but can undergo electrophilic substitution reactions and can form explosive mixtures with air under certain conditions.

1-Chloro-3-ethynylbenzene (CAS: 766-83-6) can be synthesized by the reaction of 3-ethynylbenzene with hydrogen chloride gas. This process is carried out at room temperature and atmospheric pressure, and the use of a suitable catalyst can improve the selectivity and yield of the reaction.

1-Chloro-3-ethynylbenzene (CAS: 766-83-6) is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also utilized in the production of certain polymers and as a precursor in the development of sensors and semiconductors.

When handling 1-Chloro-3-ethynylbenzene (CAS: 766-83-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety glasses. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation. In case of a spill, avoid contact with skin and eyes, and clean up using appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed emergency procedures and storage guidelines.