(2E)-2-Pentenedioic acid(CAS: 1724-02-3)

(2E)-2-Pentenedioic acid has a melting point of 145-147°C. Its molecular weight is approximately 118.11 g/mol and it has a pKa of 4.5. The compound is soluble in water and organic solvents. It is known to be moderately reactive, especially towards nucleophiles and reducing agents.

(2E)-2-Pentenedioic acid can be synthesized via several routes, including the Wittig reaction or the Diels-Alder reaction followed by hydrolysis. Commonly, the Wittig reaction involves the reaction of 2-pentenyl phosphonium salt with hydroxide in a polar aprotic solvent. These methods yield good selectivity and reasonable to good yields.

(2E)-2-Pentenedioic acid finds applications in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also used in the polymer industry for the development of special polymers, and in the chemical sensor industry for the fabrication of gas sensors. Additionally, it is used in the electronics industry for the preparation of semiconductors and other electronic components.

When handling (2E)-2-Pentenedioic acid, ensure proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a fume hood to minimize inhalation risks. Spills should be contained and cleaned up using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed emergency procedures and storage guidelines.