1,3-Dihydroxy-2-propanyl sulfanylacetate(CAS: 30618-84-9)

1,3-Dihydroxy-2-propanyl sulfanylacetate, CAS 30618-84-9, is a white to off-white crystalline solid with a molecular weight of approximately 186.23 g/mol. It is slightly soluble in water and has a melting point of about 75-77°C. The compound is reactive under basic conditions and shows good stability under acidic conditions. It has a pKa of around 12, indicating basic properties.

1,3-Dihydroxy-2-propanyl sulfanylacetate is typically synthesized via the reaction of sodium sulfide with 2-bromoacetic acid and 1,3-propanediol in the presence of a suitable base. The reaction is conducted in an aprotic solvent such as dimethylformamide (DMF) or N-methylpyrrolidone (NMP). The yield is usually around 75-85%, and the product is purified by recrystallization from water.

1,3-Dihydroxy-2-propanyl sulfanylacetate (CAS: 30618-84-9) is used in the pharmaceutical industry for the synthesis of certain drugs, particularly in peptide chemistry. It is also utilized in the polymer industry for modifying the properties of polymers, and in the sensor industry for developing gas sensors due to its reactivity with certain compounds.

When handling 1,3-Dihydroxy-2-propanyl sulfanylacetate (CAS: 30618-84-9), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate techniques, and the material safety data sheet (MSDS) should be consulted for specific instructions. If ingestion or skin contact occurs, seek medical attention immediately.