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1,3,5-Trifluorobenzene(CAS: 372-38-3)

1,3,5-Trifluorobenzene
CAS Number

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Basic Information

Molecular Formula
C6H3F3
Molecular Weight
132.08 g/mol

Physical Properties

Melting Point
−5.5 °C (lit.)
Boiling Point
76°C
Water Solubility
Insoluble in water.

Chemical Identifiers

SMILES
C1=C(C=C(C=C1F)F)F
InChIKey
JXUKFFRPLNTYIV-UHFFFAOYSA-N

Database References

MDL Number
MFCD00000333
Beilstein Registry Number
1906457

FAQ

1,3,5-Trifluorobenzene (CAS: 372-38-3) is a fluorinated aromatic compound with the chemical formula C6H3F3. It is a colorless liquid with a high melting point (43–44°C) and low solubility in water. The molecule features three fluorine atoms substituted at the 1, 3, and 5 positions of a benzene ring, contributing to its stability and unique chemical properties. It is commonly used as an intermediate in organic synthesis and has applications in various industrial processes.
1,3,5-Trifluorobenzene (CAS: 372-38-3) is widely utilized in the pharmaceutical industry as a building block for drug development, particularly in creating fluorinated compounds with enhanced bioavailability. It also serves in agrochemicals, materials science, and research for producing fluorine-containing polymers and specialty chemicals. Additionally, it is used as a solvent in certain chemical processes and as a precursor for other trifluorinated aromatic derivatives.
1,3,5-Trifluorobenzene (CAS: 372-38-3) is generally considered low toxicity when handled properly, but it requires caution. Prolonged inhalation or skin contact may cause irritation, so safety measures like gloves, ventilation, and protective eyewear are recommended. It is classified as a hazardous substance under OSHA and EPA guidelines, necessitating adherence to safety standards to minimize exposure risks. Always follow proper handling protocols to ensure workplace safety.
1,3,5-Trifluorobenzene (CAS: 372-38-3) should be stored in airtight, sealed containers in a cool (below 25°C), dry, and well-ventilated area. It is stable under normal conditions but sensitive to light, so storage in a dark place is essential. Avoid exposure to heat sources and maintain low humidity to prevent degradation. Always store it away from incompatible materials and ensure proper labeling for safe handling.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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