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6-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-N,2-dimethyl-1-benzofuran-3-carboxamide(CAS: 1194506-26-7)

6-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-N,2-dimethyl-1-benzofuran-3-carboxamide
CAS Number

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Basic Information

Molecular Formula
C21H19N3O5
Molecular Weight
393.4 g/mol

Chemical Identifiers

SMILES
CNC(=O)c1c(C)oc2c1ccc(c2)Oc1ncnc2c1cc(OC)c(c2)OC
InChIKey
BALLNEJQLSTPIO-UHFFFAOYSA-N

Database References

MDL Number
MFCD28502149

FAQ

The compound is a solid with a crystalline form. Its molecular weight is approximately 486.43 g/mol. It has a low water solubility and is slightly soluble in organic solvents. Chemically, it is highly reactive and susceptible to hydrolysis. It is also sensitive to light and air exposure.
The compound can be synthesized through a multi-step process involving the condensation of dimethyl 1-benzofuran-3-carboxylate with 6,7-dimethoxy-4-quinazolinone. This reaction is typically catalyzed by a Lewis acid such as aluminum chloride. The overall yield is moderate, around 50-60%, with good selectivity towards the desired product.
This compound is used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It may also find applications in the polymer industry for developing new materials, in sensor technology for detection purposes, and in the semiconductor industry for specific applications in manufacturing processes.
When handling this compound, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly washed down. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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