5-Azacytosine(CAS: 931-86-2)

5-Azacytosine is a modified nucleoside with the chemical formula C6H10N4O4. It functions as a DNA methyltransferase inhibitor and is characterized by its ability to induce hypomethylation of DNA, making it useful in various biological and medical applications. It is a white crystalline solid with moderate solubility in water and organic solvents.

5-Azacytosine is primarily used in pharmaceutical research as a DNA methyltransferase inhibitor, aiding in the treatment of certain cancers. It also finds applications in epigenetic studies, cell culture, and as a reagent in biochemical research. Its role in modulating gene expression makes it valuable in drug development and molecular biology experiments.

5-Azacytosine is generally considered safe when handled properly, but it can be toxic if inhaled, ingested, or exposed to skin. Safety measures include wearing protective gloves, goggles, and a lab coat, and working in a well-ventilated area. It is classified as a hazardous substance under certain safety standards and requires careful handling in laboratory settings.

5-Azacytosine should be stored in a cool, dry, and dark place, preferably at 2-8°C. It is best kept in a sealed container away from moisture and light to maintain stability. Proper storage is essential to prevent degradation and ensure its effectiveness for research or pharmaceutical use.