1-Bromo-2,3,4-trifluorobenzene(CAS: 176317-02-5)

1-Bromo-2,3,4-trifluorobenzene (CAS: 176317-02-5) is a white crystalline solid with a molecular weight of approximately 227.01 g/mol. It has low solubility in water but is soluble in organic solvents like ethanol and acetonitrile. It is a reactive brominated aromatic compound with a high affinity for halogenation reactions and electrophilic aromatic substitution. It is often used in the synthesis of pharmaceuticals and other organic compounds.

1-Bromo-2,3,4-trifluorobenzene (CAS: 176317-02-5) is typically synthesized via electrophilic aromatic substitution by brominating 2,3,4-trifluorobenzenesulfonic acid. This process uses a bromine reagent and a Lewis acid catalyst, such as aluminum bromide, to achieve high selectivity and yield. The reaction conditions are carefully controlled to avoid side reactions and ensure a pure product.

1-Bromo-2,3,4-trifluorobenzene (CAS: 176317-02-5) is used in the pharmaceutical industry for the synthesis of various drug candidates. It is also utilized in the polymer industry for the production of high-performance polymers with specific chemical properties. Additionally, it has applications in the semiconductor industry as a precursor for organofluorine compounds and in the field of sensors for its unique chemical reactivity.

When handling 1-Bromo-2,3,4-trifluorobenzene (CAS: 176317-02-5), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be stored in a cool, dry place away from direct sunlight and flammable materials. Handling should be conducted in a fume hood to minimize exposure to bromine vapor. In case of a spill, it should be cleaned up using appropriate absorbent materials and disposed of according to local waste regulations. Safety data sheets (SDS) should be consulted for detailed safety guidelines.