1H-Imidazole-1-carbaldehyde(CAS: 3197-61-3)

1H-Imidazole-1-carbaldehyde (CAS: 3197-61-3) is a crystalline solid with a molecular weight of approximately 120.10 g/mol. It has a solubility of up to 0.8 g/100 mL in water and is slightly soluble in ethanol. This compound is known for its reactivity, particularly in nucleophilic substitution reactions and as a carbonyl compound, which can undergo aldol condensation and other reactions.

1H-Imidazole-1-carbaldehyde (CAS: 3197-61-3) can be synthesized by the direct oxidation of 1H-imidazole using hydrogen peroxide in the presence of a catalyst such as sodium periodate or potassium permanganate. The reaction is carried out in a suitable solvent like water or methanol, with a yield of approximately 85-90%.

1H-Imidazole-1-carbaldehyde (CAS: 3197-61-3) is primarily used in the pharmaceutical industry for the synthesis of various drug compounds. It also finds applications in the polymer industry as a monomer for the production of functional polymers. Additionally, it is used in the development of sensors and semiconductors due to its chemical reactivity and functional groups.

When handling 1H-Imidazole-1-carbaldehyde (CAS: 3197-61-3), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat to protect against skin and eye contact. The substance should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. In the event of a spill, it should be promptly cleaned up with an appropriate solvent, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.