4-Hydroxyphthalonitrile(CAS: 30757-50-7)

4-Hydroxyphthalonitrile (CAS: 30757-50-7) is a white crystalline solid with a molecular weight of approximately 188.14 g/mol. It has a low water solubility of about 0.02 g/L. Chemically, it is relatively stable but can undergo hydrolysis under basic conditions. It has limited reactivity in neutral and acidic solutions.

4-Hydroxyphthalonitrile can be synthesized via the phthalonitrile route, involving the addition of hydroxylamine to phthalonitrile in the presence of an acid catalyst. The yield is typically around 85-90%, with good selectivity towards the desired product.

4-Hydroxyphthalonitrile (CAS: 30757-50-7) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the production of polymers and as a precursor in the manufacturing of sensors and semiconductors.

When handling 4-Hydroxyphthalonitrile (CAS: 30757-50-7), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a sealed container away from moisture and heat. Work in a well-ventilated area or fume hood to prevent inhalation. In case of a spill, neutralize with an acid before cleaning up. Always refer to the Safety Data Sheet (SDS) for detailed safety information.