3-(2-Bromo-4,5-dimethoxyphenyl)propanenitrile(CAS: 35249-62-8)

3-(2-Bromo-4,5-dimethoxyphenyl)propanenitrile (CAS: 35249-62-8) is a crystalline compound with a molecular weight of approximately 290.05 g/mol. It has a low water solubility and poor solubility in common organic solvents. The compound is relatively stable but can react with bases to form amines. It is insoluble in water but slightly soluble in ethanol and acetone.

3-(2-Bromo-4,5-dimethoxyphenyl)propanenitrile is commonly synthesized via a reaction of 2-bromo-4,5-dimethoxybenzaldehyde with propionitrile. The reaction is catalyzed by palladium or rhodium complexes, and the yield is typically around 85%. The reaction is typically performed under mild conditions, and the product is isolated by recrystallization.

3-(2-Bromo-4,5-dimethoxyphenyl)propanenitrile (CAS: 35249-62-8) is used in the pharmaceutical industry as an intermediate for drug synthesis. It is also utilized in the polymer industry for the preparation of functional polymers, and in sensor technology due to its reactivity and stability.

When handling 3-(2-Bromo-4,5-dimethoxyphenyl)propanenitrile (CAS: 35249-62-8), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. It should be stored in a fume hood or under a nitrogen atmosphere to prevent contact with moisture and air. In case of a spill, neutralize the spill with an appropriate base before cleaning up. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.