4'-Methoxyacetanilide(CAS: 51-66-1)

4'-Methoxyacetanilide (CAS: 51-66-1) is a white crystalline solid with a molecular weight of approximately 148.17 g/mol. It is slightly soluble in water but soluble in many organic solvents such as ethanol and acetone. It has a pKa of around 7.2 and is relatively stable under normal conditions. Reactivity is low, but it can undergo hydrolysis under acidic or basic conditions.

4'-Methoxyacetanilide is typically synthesized via the acetylation of p-methoxyaniline. The reaction involves treating p-methoxyaniline with acetic anhydride in the presence of a catalyst like pyridine at a suitable temperature (e.g., 50°C). This process yields a high yield of the desired product with high selectivity.

4'-Methoxyacetanilide (CAS: 51-66-1) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various analgesics and antipyretics. It is also utilized in the polymer industry for the manufacture of certain plastics and resins. Additionally, it has applications in the textile industry for dyeing and finishing processes.

Proper handling of 4'-Methoxyacetanilide (CAS: 51-66-1) requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and heat sources. Spills should be handled using appropriate absorbent materials and cleaned up according to safety data sheet (SDS) guidelines. Always refer to the SDS for detailed handling instructions and emergency procedures.