2-Chloro-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]benzenesulfonamide(CAS: 64902-72-3)

2-Chloro-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]benzenesulfonamide is a white crystalline solid with a molecular weight of approximately 419.95 g/mol. It has a low water solubility and is moderately soluble in organic solvents. This compound is reactive towards nucleophiles and exhibits poor stability under basic conditions. It is used as an intermediate in organic synthesis.

2-Chloro-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]benzenesulfonamide is synthesized through a multistep process involving the coupling of 2-chlorobenzenesulfonamide with 4-methoxy-6-methyl-1,3,5-triazine. The reaction is typically performed in the presence of a base, such as potassium carbonate, and an organic solvent like N,N-dimethylformamide (DMF). The yield is moderate, and the reaction requires precise control of temperature and reagent ratios.

2-Chloro-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]benzenesulfonamide is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various bioactive compounds. It also finds applications in the polymer industry for the development of functional materials and in the sensor industry for the fabrication of chemical sensors due to its reactivity and stability.

When handling 2-Chloro-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]benzenesulfonamide, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood due to its reactivity. Spills should be cleaned up promptly, and the area should be thoroughly decontaminated. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.