2-Bromo-3,5-dichlorobenzaldehyde(CAS: 873983-89-2)

2-Bromo-3,5-dichlorobenzaldehyde (CAS: 873983-89-2) is a crystalline solid with a molecular weight of approximately 297.03 g/mol. It has a low solubility in water but is more soluble in organic solvents such as ethanol and acetone. This compound is highly reactive, particularly towards nucleophilic substitution reactions. It is a valuable intermediate in organic synthesis due to its bromine and chlorine substituents.

2-Bromo-3,5-dichlorobenzaldehyde can be synthesized by bromination of 3,5-dichlorobenzaldehyde. Commonly, this involves treating 3,5-dichlorobenzaldehyde with bromine in the presence of a base such as sodium hydroxide. The reaction is typically carried out in a water-miscible solvent like dimethylformamide (DMF) to ensure good reactivity and selectivity. The overall yield can be up to 80%.

2-Bromo-3,5-dichlorobenzaldehyde (CAS: 873983-89-2) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It is also relevant in the polymer industry for the development of advanced materials with specific properties. Additionally, it finds applications in the semiconductor and sensor industries due to its unique chemical properties.

When handling 2-Bromo-3,5-dichlorobenzaldehyde (CAS: 873983-89-2), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a laboratory coat. Work should be conducted in a fume hood to minimize exposure to fumes. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.