4-Bromo-1-chloro-2-methylbenzene(CAS: 54932-72-8)

4-Bromo-1-chloro-2-methylbenzene (CAS: 54932-72-8) is a yellow crystalline solid with a molecular weight of approximately 226.02 g/mol. It has a density of 1.32 g/cm³ and a melting point of 51-52°C. Soluble in organic solvents like ethanol and acetone, it is slightly soluble in water. Chemically, it is reactive towards nucleophiles and electrophiles, making it useful in various synthetic transformations and reactions.

4-Bromo-1-chloro-2-methylbenzene (CAS: 54932-72-8) can be synthesized via the chlorination of 4-bromo-2-methylbenzene followed by bromination, or through bromination and subsequent chlorination of 2-methylbenzene. These reactions are typically carried out under anhydrous conditions using reagents like bromine and chlorine, with DBU as a catalyst. High selectivity and good yield can be achieved under optimized conditions.

4-Bromo-1-chloro-2-methylbenzene (CAS: 54932-72-8) is utilized in the pharmaceutical industry for the synthesis of intermediates and drugs, and in the polymer industry for the production of specialty polymers. It is also used in the electronics sector as a precursor for organic semiconductors and in the sensor industry for the fabrication of chemical and biological sensors.

Proper handling of 4-Bromo-1-chloro-2-methylbenzene (CAS: 54932-72-8) requires the use of personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. In case of a spill, handle it carefully and follow the appropriate emergency procedures. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage procedures.