(3R)-3-Amino-3-phenylpropanoic acid(CAS: 13921-90-9)

(3R)-3-Amino-3-phenylpropanoic acid is a white crystalline solid with a molecular weight of approximately 211.23 g/mol. It is slightly soluble in water and has a pKa of 2.3. This compound is reactive towards nucleophiles and can undergo various organic reactions such as esterification and amide formation.

(3R)-3-Amino-3-phenylpropanoic acid can be synthesized via a multi-step process involving the condensation of phenylacetic acid with ammonia, followed by reduction of the amide to the corresponding amine. Common catalysts include palladium on carbon, and the overall yield is around 70-80%.

(3R)-3-Amino-3-phenylpropanoic acid is primarily used in the pharmaceutical industry as a precursor for the synthesis of various drugs. It is also applied in the production of certain polymers and in the development of chemical sensors and semiconductors.

When handling (3R)-3-Amino-3-phenylpropanoic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves and goggles. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials, and the area should be flushed with water. Refer to the safety data sheet (SDS) for detailed information on handling and disposal.