(3R,4S)-4-(4-Bromophenyl)-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid(CAS: 1217829-96-3)

(3R,4S)-4-(4-Bromophenyl)-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid (CAS: 1217829-96-3) is a white or off-white crystalline solid. The molecular weight is approximately 378.2 g/mol. It has low aqueous solubility but good solubility in organic solvents like methanol and dichloromethane. It is moderately reactive and susceptible to hydrolysis under acidic conditions. This compound is often used in organic synthesis due to its stability and reactivity.

(3R,4S)-4-(4-Bromophenyl)-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid (CAS: 1217829-96-3) is synthesized by the Williamson ether synthesis followed by protection of the primary amine with tert-butoxycarbonyl (Boc) group. The bromophenyl derivative is reacted with tert-butoxycarbonyl chloride in the presence of a base to form the protected pyrrolidine-3-carboxylic acid. This method offers high yield and selectivity.

(3R,4S)-4-(4-Bromophenyl)-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid (CAS: 1217829-96-3) is primarily used in the pharmaceutical industry for the synthesis of complex organic molecules and as a key intermediate in the development of new drugs. It may also have applications in polymer synthesis and as a building block in various material science applications.

When handling (3R,4S)-4-(4-Bromophenyl)-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid (CAS: 1217829-96-3), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound is poorly soluble in water but can release volatile compounds. It should be handled in a well-ventilated area or with the use of a fume hood. In case of a spill, the area should be flushed with water and the material should be disposed of according to safety data sheet (SDS) guidelines.