(2R)-2-Amino-2-phenylacetamide(CAS: 6485-67-2)

(2R)-2-Amino-2-phenylacetamide (CAS: 6485-67-2) is a crystalline solid with a molecular weight of approximately 187.23 g/mol. It has a pKa of about 9.5 and is slightly soluble in water. This compound is relatively stable under normal conditions but can react with strong acids or bases. It is an important intermediate in the synthesis of various pharmaceuticals and agrochemicals.

(2R)-2-Amino-2-phenylacetamide (CAS: 6485-67-2) is commonly synthesized via the amidation of 2-aminophenylacetic acid with phenylacetyl chloride in the presence of a base such as triethylamine. The reaction is typically carried out in a non-polar solvent like dichloromethane. This method offers high yield and good selectivity.

(2R)-2-Amino-2-phenylacetamide (CAS: 6485-67-2) is widely used in the pharmaceutical and agrochemical industries as an intermediate. It also finds applications in the production of certain dyes and plastics. Its use in the polymer and semiconductor industries is less common but has potential for further development.

When handling (2R)-2-Amino-2-phenylacetamide (CAS: 6485-67-2), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to avoid inhalation of dust or vapors. Store the compound in a cool, dry place away from strong acids, bases, and oxidizers. Follow standard laboratory safety guidelines and consult the Safety Data Sheet (SDS) for detailed handling instructions.