4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine(CAS: 35808-68-5)

4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine (CAS: 35808-68-5) is a crystalline solid with a molecular weight of approximately 221.62 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. This compound shows moderate reactivity and is susceptible to hydrolysis in the presence of water and acidic or basic conditions.

4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine (CAS: 35808-68-5) can be synthesized via a multi-step procedure. It usually involves the condensation of 6-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-carbaldehyde with chloroacetaldehyde under basic conditions. The reaction is catalyzed by sodium hydroxide, and the product is isolated and purified through recrystallization.

4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine (CAS: 35808-68-5) is primarily used in the pharmaceutical industry for the synthesis of drugs. It is also applied in the polymer industry for the development of functional polymers with specific properties. Additionally, it has potential applications in the production of sensors and semiconductors.

When handling 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine (CAS: 35808-68-5), safety precautions include the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from sources of heat and ignition. Fume hoods should be used during handling to minimize exposure. In case of a spill, it should be immediately cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for comprehensive safety information.