(1r,4r)-6'-Fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine(CAS: 863513-91-1)

The compound (1r,4r)-6'-Fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine is a solid with a crystalline form. It has a molecular weight of approximately 417.37 g/mol. The compound is poorly soluble in water but soluble in organic solvents like DMSO and acetonitrile. It is moderately reactive, showing some tendency towards protonation and nucleophilic substitution reactions.

(1r,4r)-6'-Fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine is typically synthesized through multi-step organic synthesis involving ring closure, alkylation, and fluorination reactions. Commonly used catalysts include palladium-based catalysts with base like triphenylphosphine. The overall yield is around 60-70%, with good selectivity towards the desired product.

(1r,4r)-6'-Fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine is primarily used in the pharmaceutical industry, where it serves as a key intermediate for the development of various pharmaceutical compounds. It is also explored in the polymer industry for its potential use in developing novel materials with specific properties. Additionally, the compound may be used in sensor technology and semiconductor applications.

When handling (1r,4r)-6'-Fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a laboratory coat. The compound should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be carefully cleaned up using appropriate methods. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.