2-Methyl-2-propanyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate(CAS: 113451-59-5)

2-Methyl-2-propanyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate is a crystalline solid with a molecular weight of approximately 218.26 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and ethanol. Chemically, it is reactive towards nucleophiles and can undergo ring-opening reactions. It is stable under normal conditions but should be stored away from direct sunlight and heat sources.

2-Methyl-2-propanyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate can be synthesized using a multistep process involving the formation of a diazabicyclic ring followed by carboxylation. Commonly, the reaction involves a Grignard reagent and diazabicyclic intermediates. The synthesis typically yields 70-80% purity and requires careful control of reaction conditions to achieve the desired stereochemistry.

2-Methyl-2-propanyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate is used primarily in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for the development of specialty polymers and in the semiconductor industry for specific applications in lithography and etching processes.

When handling 2-Methyl-2-propanyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The substance should be used in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up carefully, and the material safety data sheet (MSDS) should be consulted for detailed handling procedures.