Thieno[3,2-c]pyridine-2-carboxylic acid(CAS: 86236-37-5)

Thieno[3,2-c]pyridine-2-carboxylic acid (CAS: 86236-37-5) is a crystalline solid with a molecular weight of approximately 217.22 g/mol. It is slightly soluble in water and more soluble in organic solvents like dimethylformamide (DMF) and acetonitrile. Chemically, it is reactive towards nucleophiles and can undergo condensation reactions. It is stable under normal storage conditions but should be protected from moisture and light.

Thieno[3,2-c]pyridine-2-carboxylic acid (CAS: 86236-37-5) is typically synthesized via the condensation of 2-aminothieno[3,2-c]pyridine with carboxylic acid chloride or anhydride, often under a catalytic condition with a hindered base. The yield is generally high, and the product is purified by recrystallization from appropriate solvents.

Thieno[3,2-c]pyridine-2-carboxylic acid (CAS: 86236-37-5) is used in the pharmaceutical industry for drug discovery, particularly in peptide and protein synthesis. It is also used in the polymer industry for functionalizing polymers, and in the sensor industry for developing chemical and biological sensors due to its excellent solubility and reactivity.

When handling Thieno[3,2-c]pyridine-2-carboxylic acid (CAS: 86236-37-5), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from moisture and light. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS) for specific handling and disposal instructions.