5-Bromoisoquinolin-8-amine(CAS: 90721-35-0)

5-Bromoisoquinolin-8-amine (CAS: 90721-35-0) is a crystalline solid with a molecular weight of approximately 242.04 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and methanol. This compound exhibits basic properties and reacts with acids to form salts. It is stable under normal conditions but should be protected from moisture and light.

5-Bromoisoquinolin-8-amine (CAS: 90721-35-0) is typically synthesized by bromination of 8-aminooxazolo[5,4-d]isoquinoline followed by deamination. The reaction involves the use of bromine in the presence of a suitable catalyst, such as N,N-dimethylformamide (DMF), and is carried out under anhydrous conditions to achieve high yield and selectivity.

5-Bromoisoquinolin-8-amine (CAS: 90721-35-0) finds applications in the pharmaceutical industry, particularly in the synthesis of drugs and intermediates. It is also used in the development of polymers for electronic applications and in the production of sensors for detecting various analytes. Its unique properties make it suitable for a range of industrial uses.

When handling 5-Bromoisoquinolin-8-amine (CAS: 90721-35-0), it is essential to use appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work must be conducted in a well-ventilated area or a fume hood to prevent inhalation of bromine fumes. Spills should be immediately cleaned up with the appropriate absorbent material, and proper disposal methods should be followed. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency information.