4,4-Dimethyl-3,4-dihydro-2(1H)-quinolinone(CAS: 76693-04-4)

4,4-Dimethyl-3,4-dihydro-2(1H)-quinolinone is a colorless to white crystalline solid with a molecular weight of 224.25 g/mol. It is slightly soluble in water but more soluble in organic solvents such as ethanol and acetone. This compound is known for its stability and limited reactivity under normal conditions, but it can undergo dehydrogenation to yield quinoline under specific conditions.

4,4-Dimethyl-3,4-dihydro-2(1H)-quinolinone can be synthesized via a multistep process involving the condensation of 4,4-dimethylacetophenone with an appropriate amine followed by amination and subsequent dehydration. The reaction is typically catalyzed by a Lewis acid and proceeds with good yield and selectivity.

4,4-Dimethyl-3,4-dihydro-2(1H)-quinolinone finds applications in the pharmaceutical industry, where it serves as an intermediate in the synthesis of certain drugs. It is also used in the development of sensors and as a precursor for the production of semiconductors and polymers.

When handling 4,4-Dimethyl-3,4-dihydro-2(1H)-quinolinone, it is recommended to wear appropriate personal protective equipment, including gloves, safety goggles, and a lab coat. Ensure proper ventilation and handle in a fume hood to minimize inhalation risks. In case of a spill, contain the spill using appropriate absorbent materials and follow the guidelines in the Safety Data Sheet (SDS) for disposal.