(1R,2R,4R,5R)-2-(hydroxymethyl)-4-(6-hydroxypurin-9-yl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexane-1,5-diol(CAS: 2140-11-6)

(1R,2R,4R,5R)-2-(hydroxymethyl)-4-(6-hydroxypurin-9-yl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexane-1,5-diol is a crystalline compound with a molecular weight of approximately 338.24 g/mol. It has a solubility of 0.15 g/L in water and is moderately soluble in organic solvents. The compound is known for its chemical stability and reactivity in nucleophilic substitution reactions.

(1R,2R,4R,5R)-2-(hydroxymethyl)-4-(6-hydroxypurin-9-yl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexane-1,5-diol is synthesized through a multi-step process involving the condensation of dimethyl 1,5-hydroxylactone with 6-hydroxypurine-9-yl chloride, followed by hydrogenation and hydroxylation steps. Common catalysts include platinum and palladium on carbon, with yields of up to 85%.

(1R,2R,4R,5R)-2-(hydroxymethyl)-4-(6-hydroxypurin-9-yl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexane-1,5-diol is primarily used in the pharmaceutical industry for its role as an intermediate in the production of purine-based drugs. It is also utilized in the development of sensors and semiconductors due to its unique chemical properties.

When handling (1R,2R,4R,5R)-2-(hydroxymethyl)-4-(6-hydroxypurin-9-yl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexane-1,5-diol, safety goggles and gloves are essential. This compound should be managed in a well-ventilated area or fume hood to minimize inhalation risks. Proper spill clean-up procedures should be followed, and the Material Safety Data Sheet (MSDS) should be consulted for detailed information on safe handling and disposal practices.