3,5-dimethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole(CAS: 857530-80-4)

3,5-dimethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole is a crystalline solid with a molecular weight of approximately 324.44 g/mol. It has low solubility in water but is soluble in organic solvents like DMSO. The compound exhibits moderate reactivity, particularly in reactions involving boron-containing functionalities. It is stable under normal conditions but should be stored in a cool, dry place to avoid degradation.

3,5-dimethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole is typically synthesized via a boronate ester formation reaction. This involves the coupling of a boronic acid or ester with 3,5-dimethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole using a palladium catalyst under standard cross-coupling conditions. The yield and selectivity of this reaction can be optimized by adjusting the catalyst and reaction conditions.

3,5-dimethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole is used in pharmaceuticals for the synthesis of bioactive compounds. It also has applications in polymer synthesis, where it can act as a functional monomer. Additionally, it is utilized in the development of sensors and as precursor materials in semiconductor manufacturing due to its unique boron-containing structure.

When handling 3,5-dimethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and lab coats. The compound should be stored in a fume hood or a sealed container to minimize exposure. In case of spillage, the area should be ventilated and the spill cleaned up using appropriate absorbents. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.