Hexahydro-1H-isoindole-1,3(2H)-dione(CAS: 1444-94-6)

Hexahydro-1H-isoindole-1,3(2H)-dione (CAS: 1444-94-6) is a solid compound with a crystalline form. Its molecular weight is approximately 174.20 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. It is moderately reactive, particularly with bases and can undergo ring-opening reactions. The compound is stable under normal conditions but should be stored in a cool, dry place away from strong acids and oxidizers.

Hexahydro-1H-isoindole-1,3(2H)-dione (CAS: 1444-94-6) is typically synthesized via the Michael addition of acetone to 2-aminooxyacetic acid followed by a lactamization reaction. Common catalysts include acid catalysts such as hydrochloric acid. The selectivity and yield can be improved by using appropriate solvents and reaction conditions, leading to a pure product with a high yield.

Hexahydro-1H-isoindole-1,3(2H)-dione (CAS: 1444-94-6) is primarily used in the pharmaceutical industry for the synthesis of various organic compounds and intermediates. It also finds applications in the polymer industry, where it serves as a monomer or functional group for polymerization. Additionally, it is utilized in the sensor and semiconductor industries due to its unique chemical properties.

When handling Hexahydro-1H-isoindole-1,3(2H)-dione (CAS: 1444-94-6), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to airborne particles. Spills should be immediately cleaned up using appropriate absorbents, and the area should be thoroughly washed down with water. Always consult the Safety Data Sheet (SDS) for specific handling and storage recommendations.