trans-4-Cyclohexyl-L-proline hydrochloride(CAS: 90657-55-9)

Trans-4-Cyclohexyl-L-proline hydrochloride (CAS: 90657-55-9) is a white to off-white crystalline solid. It has a molecular weight of approximately 217.75 g/mol and is slightly soluble in water. It shows basic properties due to the presence of the hydrochloride group. The compound is stable and non-flammable under normal conditions, but it is reactive towards strong bases. It is often used in pharmaceutical and chemical synthesis applications.

Trans-4-Cyclohexyl-L-proline hydrochloride (CAS: 90657-55-9) is typically synthesized via the chlorination of L-proline with hydrogen chloride in the presence of a suitable solvent such as acetonitrile. The reaction is conducted under mild conditions, and the yield is usually around 80-90%. The reaction is exothermic, and proper cooling is required to prevent the decomposition of the product.

Trans-4-Cyclohexyl-L-proline hydrochloride (CAS: 90657-55-9) finds applications in the pharmaceutical industry for drug synthesis, and in polymer science for the modification of polymers. It is used as a chiral auxiliary in the resolution of racemic mixtures and as a building block in organic synthesis. Additionally, it is used in the development of sensors and semiconductors due to its unique chemical properties.

When handling trans-4-Cyclohexyl-L-proline hydrochloride (CAS: 90657-55-9), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and heat sources. Handling should be conducted in a fume hood to minimize inhalation exposure. In the event of a spill, it should be cleaned up by a trained individual using appropriate procedures, and the area should be thoroughly ventilated. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.