4-Bromo-2-chlorobenzaldehyde(CAS: 158435-41-7)

4-Bromo-2-chlorobenzaldehyde is a crystalline solid with a molecular weight of approximately 252.03 g/mol. It is poorly soluble in water but soluble in organic solvents. Chemically, it is reactive towards nucleophiles and can undergo electrophilic aromatic substitution reactions. Its melting point is around 118-121°C.

4-Bromo-2-chlorobenzaldehyde is synthesized by the bromination of 2-chlorobenzaldehyde. This can be achieved using N-bromosuccinimide (NBS) in the presence of a radical initiator like benzoyl peroxide under UV light. The reaction is selective and yields up to 85% of the desired product.

4-Bromo-2-chlorobenzaldehyde is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the polymer industry as a monomer, and in the production of sensors and semiconductors.

Handling 4-Bromo-2-chlorobenzaldehyde requires the use of personal protective equipment (PPE) including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from ignition sources. If a spill occurs, it should be cleaned up with appropriate absorbent materials and disposed of according to local hazardous waste regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.