3-Bromo-4-fluorotoluene(CAS: 452-62-0)

3-Bromo-4-fluorotoluene (CAS: 452-62-0) is a colorless to pale yellow liquid with a molecular weight of 186.02 g/mol. It has a melting point of -37.5°C and a boiling point of 160.5°C. The compound is slightly soluble in water but miscible with organic solvents. It is moderately reactive towards nucleophiles and electrophiles, making it useful in various chemical reactions.

3-Bromo-4-fluorotoluene (CAS: 452-62-0) is commonly synthesized through a bromination reaction of 4-fluorotoluene using bromine in the presence of a Lewis acid catalyst. The reaction is typically carried out in an inert solvent like dichloromethane. The yield is usually high, and the reaction is selective, ensuring the desired brominated product is obtained.

3-Bromo-4-fluorotoluene (CAS: 452-62-0) is used in the pharmaceutical industry for the synthesis of certain drugs, as well as in the production of polymers and sensors. It also finds applications in the synthesis of organic semiconductors and in the development of new materials for electronic devices.

When handling 3-Bromo-4-fluorotoluene (CAS: 452-62-0), it is essential to use proper personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a cool, well-ventilated area and used in a fume hood. In case of a spill, gloves and safety glasses should be worn, and the spill should be carefully cleaned up according to the safety data sheet (SDS).