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(Trifluoromethoxy)benzene(CAS: 456-55-3)

(Trifluoromethoxy)benzene
CAS Number

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Basic Information

Molecular Formula
C7H5F3O
Molecular Weight
162.11 g/mol

Physical Properties

Melting Point
-49.9°C
Boiling Point
104°C

Chemical Identifiers

SMILES
C1=CC=C(C=C1)OC(F)(F)F
InChIKey
GQHWSLKNULCZGI-UHFFFAOYSA-N

Database References

MDL Number
MFCD00040832
Beilstein Registry Number
2043132

FAQ

(Trifluoromethoxy)benzene, with the CAS number 456-55-3, is an organic compound characterized by a benzene ring substituted with a trifluoromethoxy group (-O-CF3). It is a colorless liquid with low water solubility and exhibits stability under normal conditions. Its chemical formula is C7H5F3O, and it is commonly used as an intermediate in chemical synthesis due to its unique fluorinated structure and reactivity.
(Trifluoromethoxy)benzene (CAS: 456-55-3) is primarily utilized in pharmaceutical research as a key intermediate for developing drugs with enhanced metabolic stability. It also finds applications in industrial chemistry for producing fluorinated materials and in agrochemicals. Additionally, it serves as a solvent in specialized chemical processes and is studied in research for its role in fluorine-containing compound development.
Safety of (Trifluoromethoxy)benzene (CAS: 456-55-3) requires caution. It is considered toxic upon inhalation or skin contact and may irritate the respiratory system. Safety standards recommend handling in a well-ventilated area with appropriate PPE, such as gloves and goggles. It is classified as a hazardous substance, necessitating compliance with OSHA and REACH regulations to ensure proper disposal and minimize exposure risks.
(Trifluoromethoxy)benzene (CAS: 456-55-3) should be stored in a sealed, airtight container in a cool (2-8°C), dry, and dark location to prevent degradation. It is sensitive to moisture and air, so storage away from incompatible materials is essential. Maintain stability by avoiding temperature fluctuations and ensuring proper ventilation to mitigate potential hazards.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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