2-Chloro-N-(2,6-diethylphenyl)-N-(2-propoxyethyl)acetamide(CAS: 51218-49-6)

2-Chloro-N-(2,6-diethylphenyl)-N-(2-propoxyethyl)acetamide (CAS: 51218-49-6) is a white to off-white crystalline solid. Its molecular weight is 353.37 g/mol. It is poorly soluble in water but soluble in organic solvents like dichloromethane and acetone. This compound exhibits moderate reactivity, particularly towards nucleophiles and bases. It has a pKa of approximately 8.5.

2-Chloro-N-(2,6-diethylphenyl)-N-(2-propoxyethyl)acetamide (CAS: 51218-49-6) is typically synthesized via a multi-step process involving the reaction of 2-chloroacetyl chloride with 2,6-diethylphenylamine and 2-propoxyethanol. The synthesis involves a condensation reaction followed by an electrophilic aromatic substitution, yielding the desired product in moderate to good yield. Common catalysts include triethylamine and other basic reagents.

2-Chloro-N-(2,6-diethylphenyl)-N-(2-propoxyethyl)acetamide (CAS: 51218-49-6) is primarily used in the pharmaceutical industry for its medicinal properties. It is also utilized in the polymer industry for its ability to act as a cross-linking agent. Additionally, it finds application in the production of sensors and as a component in semiconductor manufacturing processes.

When handling 2-Chloro-N-(2,6-diethylphenyl)-N-(2-propoxyethyl)acetamide (CAS: 51218-49-6), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. It should be stored in a closed container in a cool, dry place, away from direct sunlight and heat sources. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.