5-Bromo-2-hydroxymethylpyridine(CAS: 88139-91-7)

5-Bromo-2-hydroxymethylpyridine (CAS: 88139-91-7) is a crystalline solid with a molecular weight of approximately 212.03 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. This compound exhibits basic properties due to the presence of the hydroxymethyl group. It is moderately reactive, particularly towards nucleophiles and electrophiles, and is often used in organic synthesis due to its functional groups.

5-Bromo-2-hydroxymethylpyridine is commonly synthesized via the bromination of 2-hydroxymethylpyridine. This process involves the reaction of 2-hydroxymethylpyridine with bromine in the presence of a suitable catalyst, such as iron(III) bromide. The reaction yields a high yield of 5-bromo-2-hydroxymethylpyridine with good selectivity, making it a versatile intermediate in organic synthesis.

5-Bromo-2-hydroxymethylpyridine (CAS: 88139-91-7) is primarily used in the pharmaceutical and chemical industries as a versatile intermediate. It finds applications in the synthesis of various organic compounds, particularly in the development of new drugs and materials. Its use in the polymer and semiconductor industries is also growing, where it serves as a precursor for functional materials.

When handling 5-Bromo-2-hydroxymethylpyridine (CAS: 88139-91-7), it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and lab coats. This compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up carefully using appropriate absorbents. Always consult the Material Safety Data Sheet (MSDS) for detailed handling and disposal instructions to ensure safety in the laboratory setting.