Cyclohexylboronic acid(CAS: 4441-56-9)

Cyclohexylboronic acid (CAS: 4441-56-9) is a white crystalline solid with a molecular weight of approximately 154.3 g/mol. It is slightly soluble in water and has good solubility in organic solvents. Chemically, it is reactive towards carboxylic acids and can participate in organoboration reactions, making it useful in organic synthesis.

Cyclohexylboronic acid is commonly synthesized via the coupling of cyclohexylboronic ester with sodium borohydride. This process involves the use of a suitable solvent and is characterized by good yield and selectivity. The reaction is typically conducted under mild conditions and in the presence of a catalytic amount of base.

Cyclohexylboronic acid (CAS: 4441-56-9) finds application in various industries, including pharmaceuticals for the synthesis of drug intermediates, polymers for functionalization, and sensors for detecting specific chemical species. It is also used in semiconductor manufacturing for cleaning and etching processes.

When handling cyclohexylboronic acid (CAS: 4441-56-9), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a laboratory coat. It should be stored in a fume hood to avoid inhalation. In case of spillage, it should be cleaned up using appropriate chemical waste disposal methods. The safety data sheet (SDS) should be consulted for detailed handling and disposal instructions.