3-Amino-2-pyridinecarboxylic acid(CAS: 1462-86-8)

3-Amino-2-pyridinecarboxylic acid is a crystalline compound with a molecular weight of approximately 177.18 g/mol. It has a pKa of around 6.8 and is soluble in water and organic solvents such as ethanol and methanol. This compound is known for its reactivity in nucleophilic substitution reactions and condensation reactions.

3-Amino-2-pyridinecarboxylic acid is commonly synthesized via the reduction of 2-pyridinecarboxaldehyde with hydrogen gas in the presence of a catalyst like palladium on carbon, followed by the addition of ammonia. The process provides good yield and selectivity, making it a reliable method for industrial production.

3-Amino-2-pyridinecarboxylic acid is widely used in the pharmaceutical industry for the synthesis of various drugs due to its aromatic and amine functionalities. It also finds applications in the polymer industry for modifying properties of polymers and in the development of sensors and semiconductors.

When handling 3-Amino-2-pyridinecarboxylic acid, appropriate personal protective equipment (PPE) such as gloves and safety goggles should be worn. This compound should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of spill, it should be handled with a fume hood and appropriate spill cleanup kits. Always refer to the Safety Data Sheet (SDS) for detailed safety information.