5-Ethyl-2,4(1H,3H)-pyrimidinedione(CAS: 4212-49-1)

5-Ethyl-2,4(1H,3H)-pyrimidinedione (CAS: 4212-49-1) is a white or slightly yellow crystalline solid. Its molecular weight is approximately 168.18 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is stable but can be easily hydrolyzed under acidic conditions. It does not react readily with strong bases or oxidizers.

5-Ethyl-2,4(1H,3H)-pyrimidinedione is typically synthesized through the one-pot debenzylation and cyclization of 2,4-bis(ethoxymethyl)-6-benzoylpyrimidine. This process uses catalytic amounts of acid and is performed at room temperature. The yield is generally high, around 75%, and the product is isolated by recrystallization from ethanol.

5-Ethyl-2,4(1H,3H)-pyrimidinedione (CAS: 4212-49-1) is used in the pharmaceutical industry for its biological activities such as potential as an antifungal agent. It is also used in the polymer industry for modifying properties of certain polymers. Additionally, it is applied in the sensor industry for developing gas sensors due to its sensitivity to certain gases.

When handling 5-Ethyl-2,4(1H,3H)-pyrimidinedione (CAS: 4212-49-1), ensure to use personal protective equipment (PPE) such as safety goggles, gloves, and lab coats. Store it in a cool, dry place away from direct sunlight and heat. Use a fume hood for all handling and preparation procedures to avoid inhalation. In case of a spill, immediately clean up using appropriate absorbents and dispose of according to local regulations. Refer to the Material Safety Data Sheet (MSDS) for detailed safety information.