2-Methyl-2-propanyl N-{[(2-methyl-2-propanyl)oxy]carbonyl}glycinate(CAS: 111652-20-1)

2-Methyl-2-propanyl N-{[(2-methyl-2-propanyl)oxy]carbonyl}glycinate is a colorless to white crystalline solid with a molecular weight of approximately 408.48 g/mol. It has a melting point of 150-152°C and a solubility of 0.012 g/100 mL in water at 20°C. This compound is known for its low reactivity under normal conditions, but it may undergo hydrolysis in basic or acidic solutions.

2-Methyl-2-propanyl N-{[(2-methyl-2-propanyl)oxy]carbonyl}glycinate can be synthesized through the reaction of 2-methyl-2-propanol with glycine in the presence of a suitable carbonylating agent, such as thionyl chloride, followed by an esterification step. The process is typically carried out under anhydrous conditions to ensure high yield and selectivity.

2-Methyl-2-propanyl N-{[(2-methyl-2-propanyl)oxy]carbonyl}glycinate finds applications in the pharmaceutical industry for its use as a chiral intermediate in the synthesis of drugs. It is also utilized in the polymer industry for its ability to improve the properties of certain polymers and in the sensor industry for its potential use in creating sensitive analytical devices.

When handling 2-Methyl-2-propanyl N-{[(2-methyl-2-propanyl)oxy]carbonyl}glycinate, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle the compound in a well-ventilated area or under a fume hood. In case of a spill, clean up using appropriate absorbent materials and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.