(2R)-3-Amino-1,2-propanediol(CAS: 66211-46-9)

The (2R)-3-Amino-1,2-propanediol (CAS: 66211-46-9) is a colorless, viscous liquid with a molecular weight of 107.12 g/mol. It has a specific gravity of 1.09 g/cm³ and a boiling point of 266.2°C. It is soluble in water and alcohols. It is known to react with acids to form salts and with aldehydes to form acylated derivatives. It is also reactive towards nucleophilic substitution reactions.

(2R)-3-Amino-1,2-propanediol can be synthesized by the reduction of 3-chloro-1,2-propanediol using a strong reducing agent like sodium borohydride. Alternatively, it can be prepared through hydrogenation of 1,3-propanedione, followed by reduction and amination. The reaction conditions include the use of a catalyst such as palladium on carbon and a base like sodium hydroxide.

(2R)-3-Amino-1,2-propanediol (CAS: 66211-46-9) is widely used in the pharmaceutical industry for the synthesis of drug intermediates and as a precursor in the production of polymers and sensors. It is also utilized in the formulation of adhesives and sealants, as well as in the production of semiconductors and electronic materials.

When handling (2R)-3-Amino-1,2-propanediol (CAS: 66211-46-9), ensure the use of proper personal protective equipment (PPE) such as gloves, safety goggles, and a laboratory coat. Store it in a fume hood or a well-ventilated area to avoid inhalation of fumes. In case of spillage, neutralize with a weak acid or base before cleaning up. Always refer to the Safety Data Sheet (SDS) for detailed information on handling, storage, and emergency procedures.