1,3-Benzothiazol-5-amine(CAS: 1123-93-9)

1,3-Benzothiazol-5-amine is a crystalline solid with a molecular weight of approximately 163.21 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol. The compound shows good reactivity with nucleophiles and can undergo substitution reactions. It is stable under normal conditions but requires protection from moisture and air.

1,3-Benzothiazol-5-amine is commonly synthesized through the reaction of aniline and benzoic acid in the presence of a suitable catalyst like p-toluenesulfonic acid. The reaction involves amide formation followed by the introduction of the benzothiazole ring. The yield is typically around 75-85% with good selectivity.

1,3-Benzothiazol-5-amine is primarily used in the pharmaceutical industry for its anti-inflammatory and anti-allergic properties. It is also utilized in the polymer industry for enhancing the stability of polymers. Additionally, it finds applications in the sensor and semiconductor industries for its electronic properties.

Proper personal protective equipment (PPE) including gloves, goggles, and a lab coat should be worn when handling 1,3-Benzothiazol-5-amine. It should be stored in a closed container in a cool, dry place away from moisture and heat sources. In case of a spill, the area should be ventilated and the spill cleaned up using appropriate methods. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.