3-Pyridinesulfonyl chloride(CAS: 16133-25-8)

3-Pyridinesulfonyl chloride is a chemical compound with the formula C5H4NO2SCl. It is a white solid that is highly reactive and hygroscopic, commonly used as an intermediate in organic synthesis. Its structure features a sulfonyl chloride group attached to the 3-position of a pyridine ring, making it valuable in pharmaceutical and research applications.

3-Pyridinesulfonyl chloride is primarily used in the pharmaceutical industry for synthesizing drugs like sulfonylureas and other bioactive compounds. It also serves as a key reagent in organic chemistry for creating sulfonamide derivatives. Additionally, it finds applications in research and industrial processes involving functional group modification and chemical intermediates.

3-Pyridinesulfonyl chloride is considered hazardous due to its potential to irritate skin, eyes, and respiratory systems. Safety precautions include wearing protective gloves, goggles, and a lab coat, as well as ensuring proper ventilation. It should be handled according to OSHA and WHO guidelines to minimize exposure risks.

3-Pyridinesulfonyl chloride should be stored in a sealed, airtight container in a cool, dry place, away from moisture and light. It is stable under normal conditions but requires protection from humidity and air to prevent degradation. Maintain storage temperature below 25°C and avoid prolonged exposure to moisture to ensure safety and efficacy.