α-Bromocinnamaldehyde(CAS: 5443-49-2)

α-Bromocinnamaldehyde (CAS: 5443-49-2) is a colorless or white crystalline solid with a pungent odor. Its molecular weight is approximately 217.01 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. Chemically, it is highly reactive, particularly towards nucleophiles and can undergo electrophilic aromatic substitution reactions.

α-Bromocinnamaldehyde can be synthesized from cinnamaldehyde by bromination using N-bromosuccinimide (NBS) in the presence of a radical initiator like AIBN. The reaction is carried out under mild conditions, and the product can be isolated by recrystallization. This method provides high yields and good selectivity.

α-Bromocinnamaldehyde (CAS: 5443-49-2) is primarily used in the fragrance and flavor industry due to its distinctive aroma. It is also utilized in the pharmaceutical industry for the synthesis of certain drugs. Additionally, it has applications in the polymer industry as a monomer and in the development of sensors and semiconductors.

When handling α-Bromocinnamaldehyde (CAS: 5443-49-2), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or a fume hood. Spills should be cleaned up immediately and with appropriate precautions. Always consult the Safety Data Sheet (SDS) for detailed information on safe handling and emergency procedures.