1-[2-Hydroxy-4-(hydroxymethyl)phenyl]ethanone(CAS: 22518-00-9)

1-[2-Hydroxy-4-(hydroxymethyl)phenyl]ethanone (CAS: 22518-00-9) is a white or off-white crystalline solid with a molecular weight of approximately 214.17 g/mol. It is slightly soluble in water and has good solubility in organic solvents like ethanol and acetone. Chemically, it is highly reactive due to the presence of hydroxyl and aldehyde groups, making it useful in various chemical reactions and applications.

1-[2-Hydroxy-4-(hydroxymethyl)phenyl]ethanone (CAS: 22518-00-9) is commonly synthesized through a condensation reaction of 2-hydroxy-4-hydroxymethylphenol with acetaldehyde. The reaction typically proceeds under basic conditions, with sodium hydroxide as a catalyst. The yield is around 70-80%, with good selectivity towards the desired product.

1-[2-Hydroxy-4-(hydroxymethyl)phenyl]ethanone (CAS: 22518-00-9) is widely used in the pharmaceutical industry for the synthesis of certain active pharmaceutical ingredients (APIs). It is also used in the polymer industry as a monomer, in sensors for detecting specific chemicals, and in semiconductors for various applications due to its chemical reactivity and structural properties.

When handling 1-[2-Hydroxy-4-(hydroxymethyl)phenyl]ethanone (CAS: 22518-00-9), it is essential to use personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a cool, dry place away from direct sunlight. Fume hoods should be used during handling to minimize inhalation. In case of spill, do not handle the spill directly; use suitable absorbents and dispose of the waste according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.