Epothilone D(CAS: 189453-10-9)

Epothilone D is a potent antimitotic agent with a unique mechanism of action. It is a secondary metabolite produced by Streptomyces cellulosus. Epothilone D exhibits anticancer properties by stabilizing microtubules, inhibiting cell division, and inducing apoptosis in tumor cells.

Epothilone D is primarily used in the treatment of various cancers, including ovarian cancer and non-small cell lung cancer. It is also used in clinical research to study its antitumor properties and explore potential applications in other cancer types.

Epothilone D can be toxic and may cause adverse effects such as myelosuppression, peripheral neuropathy, and gastrointestinal symptoms. Proper handling and storage under controlled conditions are crucial to ensure safety. Protective measures include using appropriate personal protective equipment and following laboratory safety guidelines.

Epothilone D should be stored at a temperature between 2°C and 8°C in a tightly sealed container, protected from light. It should be kept in a cool, dry place away from heat and direct sunlight. The container should be airtight and made of appropriate material to prevent degradation. Handle with care to avoid spills and ensure proper disposal according to local regulations.