8-(Bromomethyl)quinoline(CAS: 7496-46-0)

8-(Bromomethyl)quinoline (CAS: 7496-46-0) is a yellow crystalline solid with a molecular weight of approximately 229.04 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable but can react with reducing agents. The compound has a melting point of 128-130°C.

8-(Bromomethyl)quinoline can be synthesized via the reaction of 8-hydroxyquinoline with phosphorous tribromide. The process involves the substitution of the hydroxyl group with a bromomethyl group, providing high selectivity and yield. Commonly used catalysts and conditions ensure efficient conversion and purification.

8-(Bromomethyl)quinoline (CAS: 7496-46-0) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the development of sensors and as an intermediate in the production of dyes and pigments. Additionally, its unique properties make it useful in the semiconductor industry for specific applications.

When handling 8-(Bromomethyl)quinoline (CAS: 7496-46-0), appropriate personal protective equipment (PPE) should be worn, including gloves, safety glasses, and a lab coat. The compound should be handled in a well-ventilated fume hood to minimize exposure. Spills should be managed carefully using appropriate absorbents, and the area should be thoroughly cleaned. Always refer to the Safety Data Sheet (SDS) for detailed safety information and guidelines.