Methyl 3-oxo-3-(4-pyridinyl)propanoate(CAS: 829-45-8)

Methyl 3-oxo-3-(4-pyridinyl)propanoate (CAS: 829-45-8) is a crystalline compound with a molecular weight of approximately 203.19 g/mol. It is slightly soluble in water but soluble in common organic solvents such as ethanol and acetone. It is a reactive compound, particularly towards nucleophiles, and is sensitive to moisture and heat.

Methyl 3-oxo-3-(4-pyridinyl)propanoate (CAS: 829-45-8) is typically synthesized via the condensation of 4-pyridinecarboxaldehyde with methyl acetoacetate, followed by dehydration. The reaction is usually catalyzed by an acid, and the yield can be improved by using mild dehydration conditions under reduced pressure.

Methyl 3-oxo-3-(4-pyridinyl)propanoate (CAS: 829-45-8) is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the polymer industry for the production of advanced polymers with specific properties. Additionally, it can be applied in the semiconductor industry for the fabrication of electronic materials.

When handling Methyl 3-oxo-3-(4-pyridinyl)propanoate (CAS: 829-45-8), it is essential to wear appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. Operations should be conducted in a well-ventilated area or under a fume hood to minimize exposure. Spills should be handled with care, using appropriate cleanup materials, and the material safety data sheet (MSDS) should be consulted for detailed instructions.